Figure 5
From: Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects
NTG-NL Exerts Superior Anti-inflammatory Effects.
(A) Blank NLs are inert to ECs as cells treated with blank NLs exhibit neither an increase in U937 cell adhesion (with respect to control) nor a decrease in L-NIO-induced U937 cell adhesion (n = 10 fields of view). **p < 0.01; ns, no significance. (B) Addition of 5 μg/ml NTG-NL (≡0.07 μM NTG) to L-NIO-treated ECs significantly inhibits U937 cell-EC adhesion, which is comparable to the inhibition produced by a 70-fold greater dose of free NTG (5 μM). Free NTG dose of 0.07 μM does not produce a significant anti-inflammatory effect. (n = 10 fields of view). ***p < 0.001; ns, no significance. Data are expressed as mean ± SEM.
