Figure 6 | Scientific Reports

Figure 6

From: Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN

Figure 6

The PTEN may involve in the mitochondrial activity of the HepG2 cells.

(A) The OCR of ATP production was measured in HepG2 cells transfected with PTEN siRNA and it was markedly increased. The ROS production (B) and MDA content (C) were both increased in the HepG2 cells transfected with PTEN siRNA. While T-AOC (D) and SOD activity (E) were both significantly reduced in the HepG2 cells transfected with PTEN siRNA. Each data point represented the mean ± SE from three separate experiments in which treatments were performed in triplicate. *P < 0.05.

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