Figure 1 | Scientific Reports

Figure 1

From: APOE-ε4 selectively modulates posteromedial cortex activity during scene perception and short-term memory in young healthy adults

Figure 1

(a) A schematic of the one-back visual working memory task used in Task A. This comprised four conditions, scenes, faces, objects and scrambled objects and required participants to indicate when there was an immediate repeat of an item (indicated here by ‘R’). Activity for each separate stimulus condition was contrasted between APOE-ε4 carriers and APOE-ε4 non-carriers to identify regions within posteromedial cortex (PMC) sensitive to APOE-ε4 status. Scenes were created using Deus Ex (Ion Storm L.P., Austin, TX, USA, with software development package Deus Ex Software Development Kit v1112f); faces were generated with FaceGen Modeller 3.3 (Singular Inversions Inc., Toronto, ON, Canada); the objects shown in the figure are examples of the types of trials used in the task and are taken from the Hemera Photo-Objects 50,000, Volumes 1–3. (b) Examples of scene, face, object and squared blocks (baseline) odd-one-out trials from Task B (asterisks indicate the odd item). Scene photographs were taken by J.P.S.; faces are part of the Psychological Image Collection at Stirling (PICS. http://pics.stir.ac.uk/); objects are from the Hemera Photo-Objects 50,000, Volumes 1–3.

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