Table 1 The results of proteomics analysis.

From: (Z)3,4,5,4′-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level

Protein accession

Description

Treat/Control

KRT84

Keratin, type II cuticular Hb4 OS

0.646

KRT85

Keratin, type II cuticular Hb5 OS

0.654

K2C1

Keratin, type II cytoskeletal 1 OS

0.54

K22E

Keratin, type II cytoskeletal 2 epidermal OS

0.629

K2C5

Keratin, type II cytoskeletal 5 OS

0.658

K2C6B

Keratin, type II cytoskeletal 6B OS

0.647

K2C75

Keratin, type II cytoskeletal 75 OS

0.656

K2C79

Keratin, type II cytoskeletal 79 OS

0.657

HGFA

Hepatocyte growth factor activator OS

0.384

CSN7B

COP9 signalosome complex subunit 7b OS

0.408

QTRD1

Queuine tRNA-ribosyltransferase subunit QTRTD1 OS

0.41

HDHD3

Haloacid dehalogenase-like hydrolase domain-containing protein 3 OS

0.412

FUND2

FUN14 domain-containing protein 2 OS

0.437

NPA1P

Nucleolar pre-ribosomal-associated protein 1 OS

0.447

VP33A

Vacuolar protein sorting-associated protein 33A OS

0.464

RM03

39S ribosomal protein L3, mitochondrial OS

0.473

GLRX2

Glutaredoxin-2, mitochondrial OS

0.475

BMS1

Ribosome biogenesis protein BMS1 homolog OS

0.489

DDI2

Protein DDI1 homolog 2 OS

0.493

BPAEA

Bullous pemphigoid antigen 1, isoforms 6/9/10 OS

0.499

IMP4

U3 small nucleolar ribonucleoprotein protein IMP4 OS

0.501

ZN556

Zinc finger protein 556 OS

0.503

SUMO1

Small ubiquitin-related modifier 1 OS

0.526

IASPP

RelA-associated inhibitor OS

0.534

APOD

Apolipoprotein D OS

0.536

PEPL1

Probable aminopeptidase NPEPL1 OS

0.54

RM16

39S ribosomal protein L16, mitochondrial OS

0.542

YTHD1

YTH domain family protein 1 OS

0.548

VIME

Vimentin OS

0.561

THIC

Acetyl-CoA acetyltransferase, cytosolic OS

0.564

EDC3

Enhancer of mRNA-decapping protein 3 OS

0.564

RL32

60S ribosomal protein L32 OS

0.57

PSMG3

Proteasome assembly chaperone 3 OS

0.574

DCAF7

DDB1- and CUL4-associated factor 7 OS

0.575

SYLM

Probable leucyl-tRNA synthetase, mitochondrial OS

0.578

PEX3

Peroxisomal biogenesis factor 3 OS

0.58

NEC1

Neuroendocrine convertase 1 OS

0.589

CHCH1

Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS

0.591

ULA1

NEDD8-activating enzyme E1 regulatory subunit OS

0.591

SH3L1

SH3 domain-binding glutamic acid-rich-like protein OS

0.592

P5CR3

Pyrroline-5-carboxylate reductase 3 OS

0.602

NOC2L

Nucleolar complex protein 2 homolog OS

0.609

PCY2

Ethanolamine-phosphate cytidylyltransferase OS

0.61

EXOS7

Exosome complex exonuclease RRP42 OS

0.611

HEAT1

HEAT repeat-containing protein 1 OS

0.611

LCMT1

Leucine carboxyl methyltransferase 1 OS

0.611

TMSL3

Thymosin beta-4-like protein 3 OS

0.612

RCL1

RNA 3~-terminal phosphate cyclase-like protein OS

0.616

NOC4L

Nucleolar complex protein 4 homolog OS

0.617

AMPD2

AMP deaminase 2 OS

0.622

TET2

Probable methylcytosine dioxygenase TET2 OS

0.625

BRX1

Ribosome biogenesis protein BRX1 homolog OS

0.626

FRAP

Serine/threonine-protein kinase mTOR OS

0.627

ANK3

Ankyrin-3 OS

0.629

ALG13

UDP-N-acetylglucosamine transferase subunit ALG13 homolog OS

0.629

UTP15

U3 small nucleolar RNA-associated protein 15 homolog OS

0.631

CSTF1

Cleavage stimulation factor subunit 1 OS

0.633

CORO7

Coronin-7 OS

0.633

SCAM4

Secretory carrier-associated membrane protein 4 OS

0.633

KI21A

Kinesin-like protein KIF21A OS

0.634

EVPL

Envoplakin OS

0.635

RRS1

Ribosome biogenesis regulatory protein homolog OS

0.637

NHRF2

Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS

0.639

PKHD1

Fibrocystin OS

0.644

ZC3H8

Zinc finger CCCH domain-containing protein 8 OS

0.644

PTER

Phosphotriesterase-related protein OS

0.646

BL1S3

Biogenesis of lysosome-related organelles complex 1 subunit 3 OS

0.649

CHM4A

Charged multivesicular body protein 4a OS

0.65

CP088

Protein C16orf88 OS

0.65

BAX

Apoptosis regulator BAX OS

0.651

EIF1A

Probable RNA-binding protein EIF1AD OS

0.651

DLRB1

Dynein light chain roadblock-type 1 OS

0.656

NEK9

Serine/threonine-protein kinase Nek9 OS

0.657

PGTA

Geranylgeranyl transferase type-2 subunit alpha OS

0.658

TB10A

TBC1 domain family member 10A OS

0.662

TPPC5

Trafficking protein particle complex subunit 5 OS

0.663

GMDS

GDP-mannose 4,6 dehydratase OS

0.666

BIN1

Myc box-dependent-interacting protein 1 OS

0.666

CO024

UPF0480 protein C15orf24 OS

1.5

PIGS

GPI transamidase component PIG-S OS

1.504

SFRIP

SFRS2-interacting protein OS

1.507

UROK

Urokinase-type plasminogen activator OS

1.509

PRG4

Proteoglycan 4 OS

1.513

CC150

Coiled-coil domain-containing protein 150 OS

1.518

VPRBP

Protein VPRBP OS

1.522

CASP

Protein CASP OS

1.527

FNTB

Protein farnesyltransferase subunit beta OS

1.527

DCLK3

Serine/threonine-protein kinase DCLK3 OS

1.528

RNH2A

Ribonuclease H2 subunit A OS

1.531

STK25

Serine/threonine-protein kinase 25 OS

1.532

UB2R1

Ubiquitin-conjugating enzyme E2 R1 OS

1.533

PAI2

Plasminogen activator inhibitor 2 OS

1.543

CUTA

Protein CutA OS

1.546

CDK7

Cell division protein kinase 7 OS

1.547

NCOAT

Bifunctional protein NCOAT OS

1.548

RT18B

28S ribosomal protein S18b, mitochondrial OS

1.55

K0406

Uncharacterized protein KIAA0406 OS

1.55

CSN6

COP9 signalosome complex subunit 6 OS

1.551

CA050

Uncharacterized protein C1orf50 OS

1.563

TBCD

Tubulin-specific chaperone D OS

1.582

CP055

Uncharacterized protein C16orf55 OS

1.582

MAVS

Mitochondrial antiviral-signaling protein OS

1.59

JAK3

Tyrosine-protein kinase JAK3 OS

1.593

RPB1B

DNA-directed RNA polymerase II subunit RPB11-b1 OS

1.596

GNL1

Guanine nucleotide-binding protein-like 1 OS

1.6

OPRS1

Sigma 1-type opioid receptor OS

1.611

DNJC5

DnaJ homolog subfamily C member 5 OS

1.631

ECSIT

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS

1.633

CE033

UPF0465 protein C5orf33 OS

1.634

ITPA

Inosine triphosphate pyrophosphatase OS

1.635

ARL1

ADP-ribosylation factor-like protein 1 OS

1.637

T2AG

Transcription initiation factor IIA subunit 2 OS

1.638

NEUL

Neurolysin, mitochondrial OS

1.65

RB3GP

Rab3 GTPase-activating protein catalytic subunit OS

1.667

VGF

Neurosecretory protein VGF OS

1.67

NUDC2

NudC domain-containing protein 2 OS

1.671

CCD12

Coiled-coil domain-containing protein 12 OS

1.683

ENL

Protein ENL OS

1.687

RASF9

Ras association domain-containing protein 9 OS

1.691

ABR

Active breakpoint cluster region-related protein OS

1.712

NDUB1

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 OS

1.718

PAG1

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 OS

1.749

PLMN

Plasminogen OS = Homo sapiens GN = PLG PE = 1 SV = 2

1.766

RAB23

Ras-related protein Rab-23 OS

1.778

OASL

59 kDa 2 ~ −5 ~ −oligoadenylate synthetase-like protein OS

1.8

GOLI4

Golgi integral membrane protein 4 OS

1.842

RM42

39S ribosomal protein L42, mitochondrial OS

1.847

SFXN4

Sideroflexin-4 OS

1.867

UAP1L

UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS

1.872

RMD3

Regulator of microtubule dynamics protein 3 OS

1.892

FA21A

WASH complex subunit FAM21A OS

1.892

CC121

Coiled-coil domain-containing protein 121 OS

1.896

GRLF1

Glucocorticoid receptor DNA-binding factor 1 OS

1.896

MK07

Mitogen-activated protein kinase 7 OS

1.896

ZN408

Zinc finger protein 408 OS

1.896

HPS5

Hermansky-Pudlak syndrome 5 protein OS

1.918

SCOT1

Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial OS

1.944

SNF5

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS

1.97

RFIP5

Rab11 family-interacting protein 5 OS

1.974

CTGF

Connective tissue growth factor OS

2.085

NACA2

Nascent polypeptide-associated complex subunit alpha-2 OS

2.101

CE022

UPF0489 protein C5orf22 OS

2.115

T2H2L

General transcription factor IIH subunit 2-like protein OS

2.149

SNX9

Sorting nexin-9 OS

2.247

CLP1L

Cleft lip and palate transmembrane protein 1-like protein OS

2.276

PPIC

Peptidyl-prolyl cis-trans isomerase C OS

2.329

PSME4

Proteasome activator complex subunit 4 OS

2.347

RRP7A

Ribosomal RNA-processing protein 7 homolog A OS

2.422

RUSD2

RNA pseudouridylate synthase domain-containing protein 2 OS

2.504

S7A6O

Protein SLC7A6OS OS

3.013

DCTN6

Dynactin subunit 6 OS

3.233

IBP5

Insulin-like growth factor-binding protein 5 OS

4.22

APOC2

Apolipoprotein C-II OS

4.812