Figure 5 | Scientific Reports

Figure 5

From: Identifying robust communities and multi-community nodes by combining top-down and bottom-up approaches to clustering

Figure 5

Shifts within and between resting-state brain communities in Parkinson disease.

(A) Raw correlation matrices between resting state brain activity from control and Parkinson disease cohorts. Dashed lines indicate clusters identified by SpeakEasy from control-state data. Order of brain regions is identical in all matrices (reflects control-state clusters). (B) Co-occurrence matrices for controls and Parkinson disease cohorts. Entries in co-occurrence matrices count the number of times nodes (i,j) are found together in 100 replicated clustering results. (Inset) Semi-circles are scaled by volume to cluster size in control data. The difference in size of the corresponding lower semi-circles illustrates the change in average co-occurrence for each control-state cluster. Thus smaller semi-circles in disease (lower half) denote loss of coherence among members of a particular cluster. Text in semi-circles summarizes the most common regional characteristic of each cluster.

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