Figure 4
From: Controls and constrains of the membrane disrupting action of Aurein 1.2
Representative snapshots from the coarse grain simulations.
Amino acids are coloured according to their chemical nature (white, hydrophobic; green, hydrophilic; red, negatively charged; blue, positively charged). The α-helical backbone is also shown, each peptide in a different colour. (a) Side view of the membrane inserted peptide. Note that the “triangular” side chains correspond to the phenylalanine rings in a MARTINI representation. (b) Front view of a membrane inserted peptide. (c) Interaction of wild type peptides with DMPC. (d) Interaction of non-amidated peptides with DMPC. (e) interaction of wild type peptides with DMPC:DMPG (4:1) (DMPG in brown). (f) interaction of wild type peptides with DMPC:DMPG (3:2).
