Figure 6 | Scientific Reports

Figure 6

From: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer

Figure 6

AZD6244 inhibits migration rate, tube formation and cell viability in HUVEC.

The migration rate (A,B) and tube length (C,D) were remarkably reduced in AZD6244 (4 μM) treated cells when compared with that in control group. The CCK-8 assay was applied to determine cell viability of HUVEC (E). Inhibition of cell viability was observed in cells treatment with high concentration of AZD6244 for 24 hours (4 μM) and 48 hours (2, 3 and 4 μM) (A). # p < 0.05 vs. control group.

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