Table 1 Relationship between p-ERK expression and clinicopathological parameters in 90 gastric adenocarcinoma cases.

From: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer

Characteristic

Number of cases number(%)

p-ERK expression:number(%)

P value

Low

High

Total

90

48(53.3)

42(46.7)

 

Average years

62.1 ± 12.3

61.6 ± 11.5

62.5 ± 13.4

0.66

 < 65

52(57.8)

30(62.5)

22(52.4)

0.332

 ≥ 65

38(42.3)

18(37.5)

20(47.6)

Gender

 Male

53(58.9)

30(62.5)

23(54.8)

0.457

 Female

37(41.1)

18(37.5)

19(45.2)

TNM stage

 I-II

36(40)

24(50.0)

12(28.6)

0.038

 III- IV

54(60)

24(50.0)

30(71.4)

Tumor size (cm)

5.7 ± 2.7

5.3 ± 2.3

6.2 ± 2.9

0.093

 < 5 cm

35(38.9)

20(41.7)

15(35.7)

0.563

 ≥ 5 cm

55(61.1)

28(58.3)

27(64.3)

Lymphovascular Invasion

25(27.8)

9(18.8)

16(38.1)

0.041

Distant metastasis

4(4.4)

3(6.3)

1(2.4)

0.374