Figure 3

PPI sub-networks of SLE disease genes, essential targets and common targets.
(a) A highly connected cluster in the PPI network of SLE disease genes and essential targets. (b) Two disease protein clusters connected by TGFbeta. (c) Sub-network of high-degree common target, mENA. (d) Sub-network of the high-degree, common target MYD88D. Blue, the products of SLE disease genes; red, essential targets; green, common targets.