Figure 1 | Scientific Reports

Figure 1

From: TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling

Figure 1

Inhibition of the Progression of HCC In Vivo by TGF-β Blockade.

(A) Effects of EW-7197 (EW) on HCC progression in HCC mice. The sizes of liver tumors were visualized by bioluminescence analysis. The image (left) shows the tumor sizes in livers of two representative mice from each group. The plot (right) represents the quantification of bioluminescence intensity as the total flux (photons/second). (B) H&E staining of liver tissues from HCC mice. Scale bars: 100 μm. (C) Effects of EW-7197 on tumor sizes in HCC mice. (D) Effects of EW-7197 on liver weights in HCC mice. (E) Effects of EW-7197 on the body weights of HCC mice. *p < 0.05 vs. Sham, #p < 0.05 vs. Vehicle and ###p < 0.001 vs. Vehicle.

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