Figure 4 | Scientific Reports

Figure 4

From: TMEM16A/ANO1 is differentially expressed in HPV-negative versus HPV-positive head and neck squamous cell carcinoma through promoter methylation

Figure 4

TMEM16A is important for cellular survival in HPV-negative, but not HPV-positive cell lines.

(a–d) Cell survival study with varying concentrations of the small molecule inhibitor of TMEM16A, CaCCinh: The two HPV-positive cell lines, (a) 93-VU-147T and (b) SCC90, had much higher IC50s for CaCCInh than the HPV-negative cell lines, (c) FaDu and (d) PE/CA-PJ34. (e) Table comparing the IC50s of each cell line.

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