Table 2 Correlation of the level of FR isoforms with the histopathological parameters and molecular subtypes of invasive ductal carcinoma.
Parameters | Cases | FRα (ng/mg) in Tumor | pa | FRβ (ng/mg) in Tumor | pa | |
|---|---|---|---|---|---|---|
Tumor Size | ≤2 cm | 6 | 3.05 ± 1.43 | 0.491 | 1.89 ± 0.98 | |
2–5 cm | 27 | 3.56 ± 1.60 | 2.46 ± 0.99 | |||
> 5 cm | 6 | 3.92 ± 1.24 | 2.49 ± 0.70 | 0.46 | ||
Lymph Node Status | N0 | 4 | 2.93 ± 1.53 | 0.217 | 1.72 ± 0.24 | |
N1 | 10 | 3.07 ± 1.05 | 1.76 ± 0.83 | |||
N2 | 15 | 3.44 ± 1.62 | 2.45 ± 0.66 | |||
N3 | 10 | 3.62 ± 1.73 | 3.15 ± 1.06 | 0.009 | ||
Tumor Grade | GI | 10 | 3.15 ± 1.25 | 0.152 | 1.89 ± 0.67 | |
GII | 15 | 3.29 ± 1.50 | 2.33 ± 0.85 | |||
GIII | 14 | 4.41 ± 1.56 | 2.94 ± 1.06 | 0.078 | ||
Molecular Subtype | PR/ER+ | 22 | 2.92 ± 1.21 | 0.003 | 2.16 ± 0.85 | |
PR/ER− | 17 | 3.93 ± 1.52 | 2.64 ± 1.04 | 0.32 | ||
HER2+ | 7 | 2.52 ± 0.94 | 0.031 | 1.91 ± 0.78 | ||
HER2− | 32 | 3.76 ± 1.52 | 2.48 ± 0.97 | 0.188 |
