Figure 1 | Scientific Reports

Figure 1

From: Role of the clock gene Bmal1 and the gastric ghrelin-secreting cell in the circadian regulation of the ghrelin-GOAT system

Figure 1

Genetic deletion of Bmal1 abolishes circadian rhythmicity and alters food intake, ghrelin release and expression.

(a) Food intake, (b) hypothalamic relative mRNA expression levels of AgRP, (c) plasma octanoyl ghrelin levels and (d) plasma total ghrelin levels in ad libitum-fed WT or Bmal1-KO mice. (e,f) Relative mRNA expression levels of ghrelin (e) and GOAT (f) in the stomach of WT or Bmal1-KO mice (n = 7–8 mice/time point/genotype). Light and dark phases are shaded in white and gray, respectively. (AU = arbitrary unit).

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