Figure 8
From: Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays
The down-regulations of TS-15 and TS-40 in the phosphorylations of cofilin in human umbilical vein endothelial cells.
HUVEC was treated with Y27632, TS-15 or TS-40 for 2 hours. Then, the ratio of p-conflin to T-conflin of each group was normalized by the value the control. Data represented the mean ± RSD (n = 4). Statistical comparison of the data was performed by one-way ANOVA followed by Dunnett’s test. *P < 0.05 and **P < 0.01 compared to the control group.
