Table 4 Odds ratio (95%CI) of specific adverse effects between different treatment groups.

From: Effectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee

Comparisons

GI AE

CV AE

CNS AE

Infection

MU AE

Skin AE

Celecoxib vs. placebo

1.17 (1.02, 1.34)

1.12 (0.66, 1.90)

0.95 (0.81, 1.11)

1.02 (0.85, 1.21)

0.77 (0.60, 1.00)

0.84 (0.54, 1.30)

GS vs. placebo

0.83 (0.62, 1.11)

0.84 (0.54, 1.30)

0.92 (0.58, 1.44)

1.15 (0.81, 1.62)

1.33 (0.88, 2.00)

0.61 (0.32, 1.14)

CS vs. placebo

0.76 (0.56, 1.03)

1.17 (0.46, 2.98)

0.88 (0.43, 1.78)

1.08 (0.72, 1.62)

0.57 (0.10, 3.43)

1.76 (0.21, 14.73)

Celecoxib vs. GS

1.41 (0.79, 2.53)

—

—

—

—

1.75 (0.41, 7.52)

  1. GS, glucosamine; CS, chondroitin; JSW, joint space width; GI, gastrointestinal; AE, adverse events; CV, cardiovascular; CNS, central nervous system; MU, musculoskeletal.
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