Figure 3 | Scientific Reports

Figure 3

From: Tianma Gouteng Yin, a Traditional Chinese Medicine decoction, exerts neuroprotective effects in animal and cellular models of Parkinson’s disease

Figure 3

TGY alleviates the neurotoxicity induced by α-synuclein pan-neural over expression.

WT-α-synuclein was over expressed under the neuronal specific driver elav-GAL4. The flies were treated with TGY for 30 days. It was found that (A) TGY protects the flies from the impairment of motor function induced by WT-α-synuclein. (B–D) The level of WT-α-synuclein was decreased while the level of Tyrosine hydroxylase (TH), the marker protein of dopaminergic neuron, increased accordingly. *p < 0.05, **p < 0.01 and ***p < 0.001 compared with model flies without treatment. Results were obtained from three independent replicates.

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