Figure 6

TGY mitigated the rotenone induced dopaminergic neurons loss in rats.
(A) TGY significantly prevented rotational behaviors provoked by APO in 4 weeks after rotenone intoxication and (B) avoided exacerbation in 8 weeks post intoxication. (C,D) TGY alleviated the decrease of TH in SNpc as indicated by the immunoblot result (n = 3) and confirmed by (E,F) TH DAB staining data (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001 compared with rotenone-intoxicated cells without treatment.