Figure 2
SiO2 induced both p53 and PUMA expression in HPF-a.
(A) Representative Western blot showing that SiO2 induced both p53 and PUMA expression in HPF-a in a time-dependent manner. Scale bar = 10 μm. (B) Densitometric analyses of p53 and PUMA expression (n = 5). *p < 0.05 vs p53 expression on day 0; #p < 0.05 vs PUMA expression on day 0. (C) Representative immunocytochemical images showing that SiO2 increased the expression of p53 and PUMA in HPF-a. Densitometric analyses of p53 (D) and PUMA (E) expression (n = 5). *p < 0.05 vs the control group.
