Figure 7
p53 and PUMA mediated SiO2-induced HPF-a migration in a nested matrix model.
(A) Representative images showing that SiO2 induced cell migration in the nested gel matrix, which was abolished by RNAi of p53 or PUMA. Scale bar = 80 μm. Quantification of the migrated cell number from the nested gel matrix (B) and the maximum migrated distance (C) from six separate experiments. *p < 0.05 vs the corresponding control group; #p < 0.05 vs the SiO2- and control siRNA-treated group.
