Table 1 Comparison of methylation level between lung adenocarcinoma and adjacent normal tissue in each CpG site.
CpG sites | Number of pairs | Tissue types | Mean methylation level % (95% CI) |
|---|---|---|---|
CpG1 | 20 | para-tumor | 13.55 (12.70–14.45)** |
lung adenocarcinoma tissue | 19.30 (17.05–21.80)** | ||
CpG2 | 20 | para-tumor | 27.65 (25.10–30.10)** |
lung adenocarcinoma tissue | 42.85 (36.65–49.75)** | ||
CpG3 | 20 | para-tumor | 36.40 (33.70–39.15)** |
lung adenocarcinoma tissue | 60.20 (53.20–67.80)** | ||
CpG4 | 20 | para-tumor | 28.40 (25.70–31.25)** |
lung adenocarcinoma tissue | 42.25 (35.40–49.90)** | ||
CpG5,6 | 20 | para-tumor | 28.65 (26.95–30.35)** |
lung adenocarcinoma tissue | 41.50 (37.25–45.80)** | ||
CpG7 | 20 | para-tumor | 14.40 (13.05–15.80)** |
lung adenocarcinoma tissue | 27.75 (23.05–33.20)** | ||
CpG8,9,10 | 20 | para-tumor | 55.50 (53.50–57.70)** |
lung adenocarcinoma tissue | 76.50 (72.90–79.95)** | ||
CpG11 | 20 | para-tumor | 48.10 (46.65–49.60)** |
lung adenocarcinoma tissue | 64.20 (61.60–66.80)** | ||
CpG12 | 20 | para-tumor | 52.75 (50.10–55.25)** |
lung adenocarcinoma tissue | 73.35 (68.05–78.65)** | ||
CpG13 | 20 | para-tumor | 45.80 (43.85–47.85)** |
lung adenocarcinoma tissue | 58.70 (52.05–65.40)** |
