Table 3 Univariate and multivariate Cox regression analyses of overall survival in 92 NSCLC patients following surgery.

From: DNA methylation mediated silencing of microRNA-145 is a potential prognostic marker in patients with lung adenocarcinoma

Parameters

Univariate analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Age ( > 60)

1.982

1.183–3.321

0.009

1.973

1.143–3.405

0.015

Gender (male)

1.050

0.591–1.865

0.867

—

—

—

Tumor diameter ( > 3m)

1.106

0.649–1.886

0.712

—

—

—

Pleural invasion (Positive)

1.602

0.933–2.750

0.087

—

—

—

Lymph node metastasis (Positive)

2.290

1.365–3.841

0.002

1.389

0.751–2.567

0.295

TNM stage (II and III)

2.364

1.412–3.957

0.001

1.787

1.021–3.128

0.065

Histologic grade (M-L and L)

2.595

1.470–4.580

0.001

1.832

1.015–3.308

0.044

miR-145 level (Low)

2.128

1.255–3.608

0.004

1.787

1.021–3.128

0.042

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