Figure 3
From: Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis
Amelioration of liver fibrosis and fat accumulation in Gpnmb Tg mice under HFHS chow.
(a,b) Liver weight and triglyceride contents of Gpnmb Tg and WT mice under HFHS chow. (c,d) Liver fibrosis areas and serum ALT levels of Gpnmb Tg and WT mice under HFHS chow. (e) Periodic acid-Schiff (PAS) staining (left panels) and Azan-Mallory staining (right paels) of liver tissues of Gpnmb Tg and WT mice under HFHS chow. (f) Analysis of inflammation, fibrosis and fatty acid synthesis-related genes. mRNA levels of liver tissues of Gpnmb Tg and WT mice under HFHS chow by quantitative real-time PCR. All data are presented as mean ± standard deviation (SD) n = 8. *p < 0.05, **p < 0.01 vs. WT mice.
