Table 1 Quantifying X4 variants in HIV-1 quasispecies by ultra-deep pyrosequencing.
X4 input (%) | X4 quantification in X4:R5 virus mixtures (%) | ||||||||
---|---|---|---|---|---|---|---|---|---|
LAI:JR-CSF* | AFG4:AFG1* | CHS2:CHS11* | |||||||
0.5 | 0.5 | 0.0 | 0.6 | 0.7 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 |
1.0 | 1.7 | 0.0 | 1.0 | 0.9 | 1.1 | 1.0 | 0.6 | 0.5 | 0.0 |
5.0 | 2.3 | 2.6 | 2.0 | 5.3 | 5.4 | 7.1 | 5.0 | 4.2 | 5.3 |
20.0 | 9.2 | 1.8 | 2.5 | 21.4 | 23.4 | — | 30.0 | 25.2 | — |
50.0 | 57.8 | 43.9 | 40.7 | 53.2 | 56.2 | — | 56.2 | 53.1 | — |
75.0 | 73.6 | 78.3 | 79.3 | 74.3 | 70.8 | — | 80.6 | 81.6 | — |
100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | — | 100.0 | 100.0 | — |