Table 1 Relationship between SSEA-4 expression and the clinicopathological features of 99 patients with prostate cancer tissue.

From: The role of mesenchymal stem cells in promoting the transformation of androgen-dependent human prostate cancer cells into androgen-independent manner

Factor

Category

Total no. of patients

SSEA-4 negative (n = 22)

SSEA-4 positive (n = 77)

P

Age (years)

>65

43

9(40.9)

34(44.1)

0.786

 

≤65

56

13(59.1)

43(55.9)

 

Pathological stage (pT)

pT2 – pT3a

43

5(22.7)

38(49.4)

0.026*

 

pT3b

56

17(77.3)

39(50.6)

 

Lymph node status

Positive

58

18(81.8)

40(51.9)

0.012*

 

Negative

41

4(18.2)

37(48.1)

 

Tumour margins

Positive

21

8(36.6)

13(16.9)

0.049*

 

Negative

78

14(63.4)

64(83.1)

 

Capsular invasion

No invasion

66

12(54.5)

54(70.1)

0.171

 

Invasion

33

10(45.5)

23(29.9)

 

PSA concentration (ng/mL) before surgery

Median (range)

 

17.40(1.22–105)

21.59(3.38–91.45)

<0.001**

 

Mean

21.22

25.94

  

Gleason score

Gleason≤6

27

11(50.0)

16 (20.8)

0.007*

 

Gleason≥7

72

11(50.0)

61(79.2)

 

Biochemical recurrence

Yes (≥0.2 ng/mL)

76

13(59.1)

63(81.8)

0.026*

 

No (<0.2 ng/mL)

23

9(40.9)

14(18.2)