Figure 3 | Scientific Reports

Figure 3

From: Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

Figure 3

ELISA validation of candidate biomarkers.

Five of the top candidate biomarker proteins were validated by ELISA using antibodies targeting the murine proteins. Murine CK-MM was included for comparison. Individual biological replicates are shown. Error bars indicate mean +/− SEM. One-way ANOVA P values and mdx vs C57 fold changes are indicated for each protein. Bonferroni post hoc test significance values are indicated as **P < 0.01, ***P < 0.001.

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