Figure 2

The CENP-A nucleosome exhibits greater global flexibility than the canonical H3 nucleosome.
(A) The distance between the centers-of-mass (COMs) of the two dimers within the homotetramer is greater, on average, in the CENP-A nucleosome than in the H3 nucleosome. The distances between the COMs of the two dimers within the first (B) and second (C) heterotetramers are greater, on average, in the CENP-A nucleosome than in the H3 nucleosome. Specific average distances and standard deviations are included in Supplementary Table 1.