Figure 6
Vesicle exocytosis from AVA and AVE is not essential for the DAMP peak in backward motion.
(a) Baseline propensities (empty bars, measured 20–25 sec prior to the pBoc) and peak DAMP propensities (solid bars) for backward motion of wild-type and four transgenic strains with altered AVA or AVE activity. (b) The temporal dynamics of backward motion of AVA::unc-2(gf) transgenics. Both the minor (t = −8 sec) and the major (t = 2 sec) backward motion peaks are enhanced as compared to wild-type. Error bars or thin lines depict ± s.e.m. N(wild-type) = 28, N(AVE::unc-103(gf)) = 11, N(AVE::TeTx) = 11, N(AVA::TeTx) = 9 and N(AVA::unc-2(gf)) = 10 animals. Single and double asterisks denote significant differences from wild-type (p < 0.05 and p < 0.01, respectively).
