Figure 5

Studies of binding model of 15 to parallel G-quadruplex c-kit2.
(A) Plot of normalized fluorescence intensity at 375 nm of 1 μM 2-Ap individually labeled c-kit2 versus binding ratio of [15]/c-kit2], λex = 305 nm. (B) Binding model of compound 15 to parallel G-quadruplex c-kit2 (PDB ID: 2KQR).