Table 6 Stratified Analysis of 30-day, 1-year and Long-term All-cause Mortality across Several Subgroups.

From: Impact of Anemia and Dual Antiplatelet Therapy on Mortality in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents

 

Moderate-severe Anemia

Mild Anemia

No Anemia

PValue

P Interaction

30-Day overall mortality

 Age, n (%)

    

0.804

  <65 years

0 (0)

5 (1.9)

7 (0.4)

0.021

 

  ≥65 years

5 (10.0)

7 (1.5)

20 (2.0)

<0.001

 

 Gender, n (%)

    

0.705

  Men

3 (15.0)

7 (1.5)

16 (0.8)

<0.001

 

  Women

2 (4.4)

5 (1.8)

11 (1.5)

0.308

 

 Diabetes mellitus, n (%)

    

0.930

  No

4 (8.9)

9 (1.8)

20 (1.0)

<0.001

 

  Yes

1 (5.0)

3 (1.3)

7 (1.1)

0.296

 

 Renal insufficiency, n (%)

    

0.956

  No

0 (0)

7 (1.5)

10 (0.5)

0.049

 

  Yes

5(16.1)

5 (2.0)

14 (2.3)

<0.001

 

 Smoking, n (%)

    

0.586

  No

5 (9.4)

8 (1.8)

13 (1.0)

<0.001

 

  Yes

0 (0.0)

4(1.4)

13 (1.0)

0.750

 

 Acute coronary syndrome,n (%)

    

0.983

  No

1 (12.5)

2 (4.0)

0 (0)

0.001

 

  Yes

3 (5.7)

10 (1.5)

25 (1.0)

0.007

 

1-Year overall mortality

 Age, n (%)

    

0.968

  <65 years

0 (0)

7 (2.6)

11 (0.7)

0.009

 

  ≥65 years

6 (12.0)

16 (3.4)

31 (2.9)

0.001

 

 Gender, n (%)

    

0.828

  Men

4 (20.0)

15 (3.2)

28 (1.4)

<0.001

 

  Women

2 (4.4)

8 (2.9)

14 (1.9)

0.368

 

 Diabetes mellitus, n (%)

    

0.481

  No

4 (8.9)

18 (3.6)

28 (1.3)

<0.001

 

  Yes

2 (10.0)

5 (2.2)

14 (2.3)

0.071

 

 Renal insufficiency, n (%)

    

0.580

  No

1 (3.0)

14 (3.0)

20 (1.0)

0.003

 

  Yes

5 (16.1)

8 (3.2)

18 (3.0)

0.000

 

 Smoking, n (%)

    

0.344

  No

5 (9.4)

15 (3.3)

18 (1.3)

<0.001

 

  Yes

1 (8.3)

8 (2.8)

23 (1.7)

0.127

 

 Acute coronary syndrome,n (%)

    

0.366

  No

2 (25.0)

3 (6.0)

1 (0.5)

<0.001

 

  Yes

3 (5.7)

20 (3.0)

38 (1.6)

0.008

 

Long-term overall mortality

 Age, n (%)

    

0.965

  <65 years

0 (0.0)

11 (4.1)

23 (1.4)

0.008

 

  ≥65 years

9 (18.0)

51 (10.8)

67 (6.3)

<0.001

 

 Gender, n (%)

    

0.160

  Men

5 (25.0)

44 (9.5)

65 (3.3)

<0.001

 

  Women

4 (8.9)

18 (6.5)

25 (3.4)

0.036

 

 Diabetes mellitus, n (%)

    

0.725

  No

5 (11.1)

40 (7.9)

58 (2.8)

<0.001

 

  Yes

4 (20.0)

22 (9.6)

32 (5.2)

0.003

 

 Renal insufficiency, n (%)

    

0.392

  No

1 (3.0)

29 (6.2)

47 (2.3)

<0.001

 

  Yes

8 (25.8)

32 (12.7)

37 (6.2)

<0.001

 

 Smoking, n (%)

    

0.055

  No

6 (11.3)

35 (7.7)

34 (2.5)

<0.001

 

  Yes

3 (25.0)

27 (9.6)

55(4.1)

<0.001

 

 Acute coronary syndrome,n (%)

    

0.225

  No

2 (25.0)

7 (14.0)

2 (1.0)

<0.001

 

  Yes

6 (11.3)

54 (8.2)

81 (3.4)

<0.001

 
  1. *Probability values for interaction between the effects of anemia and patients characteristics are shown for age (≥65 years), female patients, diabetes mellitus, renal insufficiency, smoking and acute coronary syndrome (ACS).
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