Figure 2
From: Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging
Size distribution and thermosensitivity of NLP and CLP liposomes.
(a) The size of the liposome was measured with dynamic light scattering. Intensity plots showing the average hydrodynamic diameters of NLP and CLP to be 86 nm and 109 nm respectively. (b) NLP-containing calcein was heated at different temperatures. The fluorescent intensity starts to increases around 37–38 °C indicating lipid rearrangement and further increases until around 39 °C. No significant further increase is visible upon addition of the lysis reagent triton X-100. (c) Differential scanning calorimetry (DSC) showing that NLP has a transition temperature of 42 °C.
