Figure 5

Statistical parametric map for uncorrected z-values.

Left panel: Z-statistic parametric map from a mixed effects analysis of 6 mice in response to heat stimulation of the plantar hindpaw (p < 0.05, not corrected for multiple comparisons). The map shows significance patterns (below the statistical threshold shown in Fig. 4) in large areas of the brain. Anatomical areas, which were used as ROIs for signal intensity extraction are contoured. Right panel: Relative signal intensity change over time for defined anatomical brain regions (mean ± 2 s.e.m.). Plotted cortical structures are primary visual cortex, monocular area (V1), cingulate cortex, area 24a (A24a) and dorsal subiculum (DS). Plotted subcortical structures are central amygdaloid nucleus (Ce) and fornix (fx), which is a fiber group.