Figure 2
From: The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines
Duplications found in hESC lines that are present on the DGV.
(A) Chromosome 6 ideograms from SNP array analysis of MasterShef3 revealed a 267 kb duplication near the telomere, which contained 3 genes, MLLT4, KIF25, and FRMD1. Duplications of this size, or greater, have been reported and annotated on the DGV with an estimated frequency of 2.82% in the human population. (B) A 144 kb duplication was observed on chromosome 12p13.31 of RC17 hESCs. This region contained two genes, SCL2A14 and SLC2A3 and is represented on the DGV (3.9% frequency in humans).
