Figure 6 | Scientific Reports

Figure 6

From: Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease

Figure 6

The therapeutic effects of avermectin analogues to reduce lipid accumulation were dependent on FXR.

(a) Oil Red O staining of liver sections (original magnification, ×200). (b) Food intake. (c) Hepatic triglyceride. (d) Serum triglyceride. (e) Serum cholesterol. (f) Serum glucose. WT, Wild type C57BL/6J mice; KO, FXR knockout mice. n = 6 per group, Values are the means ± SEM. *p < 0.05 and ***p < 0.001 versus vehicle.

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