Table 1 Viability of P. aeruginosa PAO1 persister cells isolated from stationary cultures after treatment with GM-CSF and/or selected antibiotics.

From: Human Granulocyte Macrophage Colony-Stimulating Factor Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa Persister Cells

Antibiotic

Change in viability (compared to antibiotic alone)

GM-CSF Concentration

 

0 pM

0.17 pM

1.7 pM

17 pM

No antibiotic

−

NC

NC

NC

Ciprofloxacin (5 μg/mL)

NC

−61.5 ± 14.5% **

−53.8 ± 16.1%**

−74.0 ± 2.9%***

Tobramycin (5 μg/mL)

NC

−77.1 ± 2.0%***

−82.7 ± 2.3%***

−86.5 ± 1.7%***

  1. **p < 0.01, ***p < 0.001, one-way ANOVA followed by Tukey test. NC: No significant change.
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