Table 1 Comparison of clinical and echocardiographic characteristics according to tertile of LA strain.
Characteristics | Tertile 1 (LA strain | Tertile 2 (LA strain: | Tertile 3 (LA strain | P | All patients |
---|---|---|---|---|---|
>17.75%, n = 63) | 13.60–17.75%, n = 63) | <13.60%, n = 64) | (n = 190) | ||
Age (year) | 68 ± 10 | 71 ± 9 | 72 ± 10* | 0.025 | 70 ± 10 |
Male gender | 41 (65%) | 39 (64%) | 48 (75%) | 0.438 | 67% |
Diabetes mellitus | 18 (29%) | 20 (32%) | 14(22%) | 0.444 | 27% |
Hypertension | 40 (63%) | 42 (67%) | 43 (67%) | 0.894 | 66% |
CAD | 4 (6%) | 3 (5%) | 13 (20%)*# | 0.007 | 11% |
Stroke | 7 (11%) | 11 (17%) | 15 (23%) | 0.186 | 17% |
CHF | 8 (13%) | 19 (30%)* | 27 (42%)* | 0.001 | 29% |
CHA2DS2-VASc score | 2.83 ± 1.80 | 3.56 ± 1.83 | 3.80 ± 1.66* | 0.006 | 3.39 ± 1.80 |
SBP (mmHg) | 133 ± 22 | 128 ± 17 | 136 ± 19 | 0.085 | 133 ± 20 |
DBP (mmHg) | 78 ± 12 | 76 ± 12 | 78 ± 14 | 0.569 | 77 ± 12 |
Heart rate (min−1) | 77 ± 17 | 86 ± 20* | 86 ± 22* | 0.018 | 83 ± 20 |
Body mass index (kg/m2) | 26.6 ± 3.8 | 26.3 ± 4.4 | 25.7 ± 4.2 | 0.450 | 26.3 ± 4.1 |
Triglyceride (mg/dL) | 123 ± 95 | 111 ± 56 | 133 ± 80 | 0.421 | 123 ± 79 |
Total cholesterol (mg/dL) | 169 ± 32 | 174 ± 34 | 176 ± 41 | 0.576 | 173 ± 36 |
Medications | |||||
 ACEI and/or ARB use | 32 (51%) | 34 (54%) | 38 (59%) | 0.617 | 54% |
 β-blocker use | 29 (46%) | 27 (43%) | 27 (42%) | 0.897 | 44% |
 CCB use | 24 (38%) | 26 (41%) | 15 (23%) | 0.077 | 34% |
 Diuretics use | 25 (40%) | 22 (35%) | 33 (52%) | 0.147 | 42% |
 Antiplatelet use | 41 (65%) | 35 (56%) | 36 (56%) | 0.479 | 59% |
 Anticoagulant use | 11 (17%) | 20 (32%) | 24 (38)* | 0.038 | 29% |
Echocardiographic data | |||||
 LAVI (ml/m2) | 43 ± 16 | 44 ± 15 | 56 ± 24*# | <0.001 | 48 ± 20 |
 LVEDD (mm) | 50 ± 7 | 51 ± 7 | 54 ± 9* | 0.005 | 52 ± 8 |
 LVESD (mm) | 32 ± 7 | 36 ± 8 | 39 ± 11* | <0.001 | 36 ± 9 |
 LVMI (g/m2) | 127 ± 36 | 129 ± 35 | 155 ± 43*# | 0.001 | 137 ± 40 |
 LVEF (%) | 62 ± 10 | 56 ± 12 | 46 ± 16*# | <0.001 | 55 ± 14 |
 E (cm/s) | 98 ± 21 | 96 ± 21 | 96 ± 25 | 0.859 | 97 ± 23 |
 EDT (ms) | 152 ± 45 | 143 ± 38 | 152 ± 53 | 0.451 | 149 ± 46 |
 E’ (cm/s) | 10.3 ± 2.5 | 8.9 ± 1.7* | 7.4 ± 1.9*# | <0.001 | 8.8 ± 2.4 |
 E/E’ | 10.1 ± 3.8 | 11.3 ± 3.8 | 13.8 ± 5.2*# | <0.001 | 11.8 ± 4.5 |
 LA strain (%) | 22.02 ± 3.73 | 15.65 ± 1.21* | 11.14 ± 1.98*# | <0.001 | 16.24 ± 5.14 |
 E/LA strain (m/s) | 4.53 ± 1.14 | 6.21 ± 1.53* | 8.81 ± 2.61*# | <0.001 | 6.53 ± 2.57 |