Figure 3
Increased levels of TSPO expressed in HSCs and macrophages from liver tissues after CCl4 treatment.
Triple immunofluorescence labelling of TSPO (A., green), α-SMA (B., pink), CD11b (C., red) and DAPI (blue) in liver sections from control animals and animals treated with CCl4 for 2, 4, 6, or 8 weeks (A–E). (D,E) show merged images of (A,B) and of (A,C), respectively. The dotted line square in each slide (D,E) is enlarged and shown in the inset with DAPI. Arrowheads point to TSPO double-stained HSCs (α-SMA-positive cells). Arrows point to TSPO double-stained macrophages (CD11b-positive cells). Abbreviations: C, central venule; P, portal tract. Scale bar: 50 μm.
