Figure 4 | Scientific Reports

Figure 4

From: Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis

Figure 4

Distributions of radioactivity and TSPO expression in control and CCl4-treated rat livers.

Autoradiographic images of liver sections 1 h after injection of [18F]FEDAC are shown in (A) and (B) for control rats and rats treated with CCl4 for 6 weeks, respectively. Immunofluorescence staining of TSPO using the same sections as in (A) and (B) are shown in (C) and (D) for control rats and rats treated with CCl4 for 6 weeks, respectively. The distribution of radioactivity from [18F]FEDAC correlated well with the netlike appearance of TSPO expression in the hepatic lobules (B,D). Scale bar: 1 mm.

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