Figure 4
From: Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X
Age-dependent neuron loss in hippocampus of Tg4-42hom mice.
Quantification of neurons in the CA1 using unbiased stereology. Tg4-42hom show an age dependent reduction in number of neurons in the CA1 region, which is significant at 5 m, 6 m, 7 m and 8 m. One-way analysis of variance (ANOVA) followed by Bonferroni multiple comparisons; n = 4–8; ***p < 0.001; data presented as mean ± S.E.M; m = months.
