Table 4 Association between receipt of antibiotics according to ARUSC’s recommendations and 30-day all-cause mortality risk, according to age group, October 1, 2011 to September 30, 2012.

From: Mortality Benefits of Antibiotic Computerised Decision Support System: Modifying Effects of Age

Analysis and receipt of antibiotics according to ARUSC’s recommendations

Age < = 65 years

Age > 65 years

P-interactiona

OR

(95% CI)

OR

(95% CI)

Unadjusted analysis

 Non-receipt

1.00

Referent

1.00

Referent

0.0187

 Receipt

0.52

(0.26–1.05)

1.29

(0.97–1.72)

Adjusted analysisb

 Non-receipt

1.00

Referent

1.00

Referent

0.0302

 Receipt

0.45

(0.20–1.00)

1.28

(0.91–1.82)

  1. Abbreviations: OR, odds ratio; CI, confidence interval.
  2. aMultiplicative scale.
  3. bAdjusted using a propensity score derived from diagnosed infection, time and day of antibiotic prescription, hospitalisation days prior to antibiotics, prior hospitalisation and prior antibiotics and further adjusted for prescribing physician’s seniority and patient’s gender, ethnicity, resident status, ward class, Charlson’s comorbidity index >5 and ICU admission.