Figure 3 | Scientific Reports

Figure 3

From: Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility

Figure 3

Enhancer scanning at the 11q23.3 locus in U87MG cells.

U87MG cells were transfected with luciferase constructs for enhancer elements (A,D) or repressor elements (B,E). Tiles with enhancer activity were evaluated for allele-specific activity (C,F), with SNP minor alleles to the right of their corresponding reference tile. (A,B,D,E) *significant enhancer activity; #significant repressor activity. (C,F) *significant difference between major and minor allele. (p < 0.05)

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