Figure 5

Activity of QiBaoMeiRan formula extract (QBMRE) on estrogen receptor (ER) α/β -estrogen response element (ERE) luciferases reporter gene expression.
(A) The effect of QBMRE on ER α/β - ERE luciferases reporter gene expression in HEK293 cells. (B) The effect of the combination of QBMRE and E2 on ER α/β - ERE luciferases reporter gene expression in HEK293 cells. Data are the mean ± standard deviation of quadruplicate analyses, expressed relative to that of treatment with 0.1% DMSO. *p < 0.05, **p < 0.01 compared to DMSO; #p < 0.05, ###p < 0.001, compared to 0.01 μM E2. (▲▲▲) p < 0.001, (▲▲▲) p < 0.01, (▲) p < 0.05, compared with ERα-ERE luciferases reporter gene expression relative increase to Control.