Table 1 Univariate and Multivariate Analysis to Identify Predictors of Tumor Regression in Patients with Neoadjuvant Chemotherapy.
Variables | Univariate | analysis | Multivariate analyses | |||
|---|---|---|---|---|---|---|
Grade3and4 | Grade0-2 | P | HR | 95% CI | P | |
Gender | 0.553 | NA | NA | NA | ||
Female | 22 | 26 | ||||
Male | 60 | 70 | ||||
Age | 0.620 | NA | NA | NA | ||
≤60 | 60 | 66 | ||||
>60 | 22 | 30 | ||||
BMI | 0.195 | NA | NA | NA | ||
≤20 | 13 | 23 | ||||
>20 | 69 | 73 | ||||
Anemia | 0.603 | NA | NA | NA | ||
Yes | 22 | 22 | ||||
No | 60 | 74 | ||||
CEA(ng/ml) | 0.195 | NA | NA | NA | ||
≤20 | 74 | 80 | ||||
>20 | 8 | 16 | ||||
CA72-4(U/ml) | 0.302 | NA | NA | NA | ||
≤6 | 72 | 78 | ||||
>6 | 10 | 18 | ||||
AFP(ng/ml) | 0.001 | 0.134 | 0.029 ~ 0.616 | 0.010 | ||
≤20 | 80 | 79 | ||||
>20 | 2 | 17 | ||||
CA19-9(U/ml) | 0.826 | NA | NA | NA | ||
≤37 | 70 | 84 | ||||
>37 | 12 | 12 | ||||
Tumor location | 0.740 | NA | NA | NA | ||
Upper body | 20 | 25 | ||||
Middle body | 23 | 27 | ||||
Lower body | 28 | 36 | ||||
Diffuse type | 11 | 8 | ||||
Tumor differentiation | 0.002 | 0.404 | 0.203 ~ 0.792 | 0.008 | ||
Differentiated | 63 | 52 | ||||
Undifferentiated | 19 | 44 | ||||
Borrmann type | 0.071 | NA | NA | NA | ||
I | 18 | 11 | ||||
II | 32 | 38 | ||||
III | 21 | 39 | ||||
IV | 11 | 8 | ||||
Clinical T classification | 0.296 | NA | NA | NA | ||
cT2 | 23 | 34 | ||||
cT3 | 34 | 42 | ||||
cT4 | 25 | 20 | ||||
Clinical N classification | 0.010 | NA | NA | NA | ||
cN− | 33 | 58 | ||||
cN+ | 0.016 | 2.148 | 1.138 ~ 4.053 | 0.018 | ||
Preoperative Chemotherapy | 49 | 38 | ||||
Intravenous chemotherapy | 36 | 60 | ||||
Arterial infusion chemotherapy | 46 | 36 | ||||
