Figure 4
From: Distinct predictive performance of Rac1 and Cdc42 in cell migration
Predictions of macroscopic cell migration based on Cdc42 activity.
Macroscopic cell migration is reconstructed/predicted from Rac1 (a,b) and Cdc42 (c,d) activity. Migration direction (a,c) and migration speed (b,d) are quantified as the direction and speed of the movement of cellular centroid, respectively. The time-series were divided into two parts; the first half and last half of the data were used for estimating the response function and testing it, respectively. The blue and red lines in each panel show observations and reconstructions (before the black dotted vertical line, first half of the data) or predictions (after the black dotted vertical line, last half of the data), respectively. r is the correlation coefficient between the observations and reconstructions/predictions (see Materials and Methods) over the entire time series.
