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Figure 1

From: Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy

Figure 1

Follistatin expression induces profound skeletal muscle hypertrophy in vivo.

The effect of rAAV:Fst on TA (A) and EDL (B) muscle mass when measured 1, 2, 4, 8 and 12 weeks after vector administration. *Significantly different from muscles receiving control vector (rAAV:MCS) at the same time point (p < 0.05); #TA muscle mass in the rAAV:Fst group is significantly greater than the preceding week (p < 0.05), except for weeks 4–8 in (B).

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