Figure 7

Effect of M1 selective antagonist pirenzepine (10 nM), M3 selective antagonist p-fluoro-hexahydrosila-difenidol (p-F-HHSiD, 10 nM) and PLC inhibitor (U73122, 10 nM) after 24 hours of exposure to 10−3 M AEME (n = 4).
Potassium chloride (250 mM) was used as a positive control of neuronal death. ***p < 0.001, compared with neurobasal medium (control group), #p < 0.05, ##p < 0.01, ###p < 0.001compared with 10−3 M AEME (ANOVA and Newman-Keuls multiple comparison).