Figure 6 | Scientific Reports

Figure 6

From: Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics

Figure 6

Levels of PCSK9 in NTD maternal serum.

(a) PCSK9 concentrations in the serum of women with healthy fetuses at different GAs. (b) PCSK9 levels in the sera of women with fetuses with NTDs and healthy fetuses at different GAs (GA 15–20 w, 23–27 w, 37–40 w). (c) ROC analysis for PCSK9 to discriminate NTDs from controls. **p < 0.01.

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