Figure 4 | Scientific Reports

Figure 4

From: Leveraging a Multi-Omics Strategy for Prioritizing Personalized Candidate Mutation-Driver Genes: A Proof-of-Concept Study

Figure 4

Expression patterns of somatic mutations at the transcriptome and proteome levels.

(a) A scatter plot matrix indicated four categories of somatic mutations according to the allelic fraction. Different colors represent different clusters. Cluster_nTCM (blue), tumor-mutated alleles with a moderate allelic fraction that were not transcribed; Cluster_nTCS (green), tumor-mutated alleles with a small allelic fraction that were not transcribed; and Cluster_nTL (black), tumor-mutated alleles that were not translated; and Cluster_TL (red), tumor-mutated alleles that were translated. (b) Boxplot of allelic fractions at different levels according to clusters.

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