Figure 4
Typical visible and FTIR images of an SP in brain tissue derived from the patient who had AD pathology.
Shown from left to right are a microscope image, the amount of total proteins, the proportion of β-sheet structures and the amount of lipids. The colour bar indicates low (blue) to high (red) contents. The area in the visible image was scanned with 5-μm steps (16 × 8 pixels = 80 × 40 μm2). Scale bar, 10 μm. Protein-rich regions correspond well to the regions stained with Congo red. The proportion of β-sheet structures is high in the core of the plaque. Lipids exist around the core of the plaque.
