Figure 1 | Scientific Reports

Figure 1

From: Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms

Figure 1

Schematic illustration of the standard workflow utilized in this study.

This workflow is composed of the following four steps. 1) Retrieve protein targets from the PubChem database and their interaction proteins from the STRING database. 2) Visualise the AA-specific gene network (APN) using Cytoscape v 2.8.2. 3) Validate the genes associated with AA through literature retrieval, network analyses and experimental verification. 4) Engage in functional enrichment analysis of biological processes (BPs) and pathway analysis.

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