Figure 2
From: Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease
Increased serum hexoses in BU patients mirror decreased hexose concentrations in mycolactone-exposed cells.
(a) Differential serum levels of the detected hexoses in BU patients versus controls, shown as box and whiskers and in the context of energy-generating metabolic pathways. Biochemicals in bold red were relatively increased in patients versus controls. Those in bold black were detected at comparable levels. Those in grey were not detected. (b) Differential concentrations of detected hexoses in mycolactone- and vehicle-treated Jurkat T cells, shown as box and whiskers. *p < 0.05, ***p < 0.001.
